Dateline Oct 4, 1966: The New York Daily News gossip column reported a girl was making the rounds in Manhattan clubs who admitted to being a man in 1965. She had undergone a sex-change operation in Baltimore at the Johns Hopkins gender clinic.
By 1979, thirteen years later, enough gender surgeries had been performed to evaluate the results. It was time for a report card based on actual patients.
A 2014 study found 62.7% of patients diagnosed with gender dysphoria had at least one co-occurring disorder, and 33% were found to have major depressive disorders, which are linked to suicide ideation. Another 2014 study of four European countries found that almost 70% of participants showed one or more Axis I disorders, mainly affective (mood) disorders and anxiety.
In 2007, the Department of Psychiatry at Case Western Reserve University in Cleveland, Ohio, committed to a clinical review of the comorbid disorders of the last 10 patients interviewed at their Gender Identity Clinic. They found that “90% of these diverse patients had at least one other significant form of psychopathology . . . [including] problems of mood and anxiety regulation and adapting in the world. Two of the 10 have had persistent significant regrets about their previous transitions.”